The on-going research carried out by the Yamamoto Research R&D team has resulted in Ansitex, a dietary supplement developed to improve mood, reduce anxiety and support mental well-being and relaxation. The raw materials chosen for the manufacture of Ansitex, namely Bluenesse® Lemon Balm extract, Moodreal® Saffron extract and magnesium in bisglycinate form, are certified for their quality and act synergistically to support psychological function and counteract anxiety-related symptoms.
Modern life consistently demands outstanding performance and fast delivery times and we are overwhelmed by deadlines, thoughts and judgements. As a result, we can easily experience periods of high psycho-physical and emotional stress. In the long run, it becomes difficult to maintain the pace of work and our daily activities without being overwhelmed by anxiety and worries. Although the exact factors that trigger anxiety disorders have not yet been established, the scientific community is of the opinion that a combination of genetic, social, biological and psychological causes are to blame, and certain conditions and experiences (such as traumatic events) can act as triggers for these disorders. As always, nature provides us with various phytoextracts that can promote relaxation and mental well-being, and improve levels of uptake of the hormone serotonin, which is responsible for mood and can combat anxiety and depressive symptoms.
More specifically, Ansitex is composed of extracts of Lemon Balm, Saffron and magnesium in bisglycinate form, phytoextracts that act in synergy to support our mental well-being.
Lemon balm is an edible herbaceous plant, traditionally used to restore calm and peace of mind, and more specifically Bluenesse® Lemon Balm is a patented plant extract, obtained from the dried, water-extracted leaves. This process makes it rich in bioactive compounds, flavonoids and polyphenolic acids, organic molecules with a positive effect on the human organism that can help support cognitive performance, cope with stress and aid relaxation.
Although Saffron is a spice known for its use in cooking, it has also been used in traditional medicine since antiquity to improve mood. Patented Moodreal® saffron, which provides 2% safranal as well as crocin and picrocrocin, bioactive compounds known for their mood-enhancing action, is able to affect the serotonin levels in the body. Serotonin is a hormone that influences mood, satiety, appetite, compulsivity and anxiety, and saffron has been shown in several studies to inhibit serotonin reuptake by blocking its SERT transporter: thus, more serotonin is released in the brain, and this facilitates the induction of a state of well-being and good mood.
The formula is supplemented with Magnesium, a mineral that is known to help maintain serenity and positivity, restore good mood by counteracting stress, anxiety and mood swings, and can also aid concentration and memory. This valuable mineral stimulates serotonin production and nerve function, which promotes impulse transmission. It is also indicated during premenstrual syndrome where, due to hormonal imbalances, magnesium levels are physiologically lowered, resulting in feelings of inadequacy and depression. In its bisglycinate form, magnesium is found bound to two glycine molecules, and thus appears to be absorbed and released into the blood stream more easily than that from other sources.
Scientific references
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Lopresti AL, Drummond PD. Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action. Hum Psychopharmacol. 2014 Nov;29(6):517-27. doi: 10.1002/hup.2434. Epub 2014 Sep 22. PMID: 25384672.
Sharma N, Nachane H, Sasikumaran A, Andrade C. Saffron vs sertraline for depression in the elderly. Psychiatry Res. 2020 Mar;285:112733. doi: 10.1016/j.psychres.2019.112733. Epub 2019 Dec 13. PMID: 31866089.
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